OHSU in the news

OHSU receives $6.9 million to expand research on workplace safety and wellness

State of Reform September 30, 2021
The National Institute for Occupational Safety and Health awards $6.9 million to the Oregon Healthy Workforce Center at OHSU. This grant renews a five-year grant aimed to expand research into health care worker burnout and well-being, firefighter work schedules and chronic pain among home care workers.

Gene editing gave this blind woman some of her vision back

The Daily Beast September 30, 2021
“With any kind of new therapy being used on the human body for the first time, you always have to be cautious,” said Mark Pennesi, an ophthalmologist at the Casey Eye Institute at the Oregon Health & Science University who led the experiment. “There's the things you might know, and then there are the things you don't know. You have to always take a cautious approach.”

After long wait, Editas reveals first data for CRISPR gene editing treatment

BioPharma Dive September 29, 2021
A clinical trial evaluating a CRISPR-based gene editing technology to remove gene mutations that cause a form of blindness sees success. OHSU's Mark Pennesi, M.D., Ph.D., describes how two trial participants have experienced improved eyesight, including OHSU participant Carlene Knight who says she can now see more clearly.

Editas early data for CRISPR therapy EDIT-101 shows efficacy “signals” in two patients

Generic Engineering & Biotechnology News September 29, 2021
“I am encouraged by these initial results, which indicate this investigational gene editing treatment has been well-tolerated in this trial’s participants thus far and may also help improve sight for people with mutations in the CEP290 gene,” stated Mark Pennesi, MD, PhD, of Oregon Health & Science University, where he is a Professor of Molecular and Medical Genetics, Kenneth C. Swan Endowed Professor of Ophthalmology, and Paul H. Casey Ophthalmic Genetics Division Chief for OHSU’s Casey Eye Institute.

A gene-editing experiment let these patients with vision loss see color again

NPR's Science Friday September 29, 2021
In coverage of initial results for a clinical trial evaluating a CRISPR-based gene editing technology to remove gene mutations that cause a form of blindness, OHSU's Mark Pennesi, M.D., Ph.D., describes how two trial participants have experienced improved eyesight, including OHSU participant Carlene Knight who says she can now see more clearly.
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